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Field trials of ephemeral fever vaccines

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Vanselow, B.A., Walthall, J.C. and Abetz, I. (1995) Field trials of ephemeral fever vaccines. Veterinary Microbiology, 46 (1-3). pp. 117-130. ISSN 0378-1135

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Article Link: https://doi.org/10.1016/0378-1135(95)00077-N


Various bovine ephemeral fever (BEF) vaccines were tested between 1982 and 1984 in 24 Queensland herds; neutralising antibody responses were monitored and six of the herds were closely observed following natural challenge with ephemeral fever. A vaccine regime of two consecutive vaccinations with attenuated virus combined with the adjuvant Quil A provided excellent protection against BEF for at least 12 months, whereas one vaccination with the Quil A vaccine or two vaccinations with vaccine containing the adjuvant aluminium hydroxide gel did not provide significant protection. Antibody responses were highest for the vaccine incorporating Quil A when it was given as two consecutive injections. There was an apparent relationship between neutralising antibody response and the level of protection.

Item Type:Article
Keywords:ephemeral fever, vaccines
Subjects:Science > Microbiology > Immunology
Veterinary medicine > Veterinary virology
Veterinary medicine > Diseases of special classes of animals > Cattle
Live Archive:19 Apr 2024 03:59
Last Modified:19 Apr 2024 03:59

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