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Bats are natural reservoirs of SARS-like coronaviruses

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Li, W., Shi, Z., Yu, M., Ren, W., Smith, C., Epstein, J. H., Wang, H., Crameri, G., Hu, Z., Zhang, H., Zhang, J., McEachern, J. A., Field, H., Daszak, P., Eaton, B. T., Zhang, S. and Wang, L.-F. (2005) Bats are natural reservoirs of SARS-like coronaviruses. Science, 310 (5748). pp. 676-679. ISSN 1095-9203

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Article Link: https://doi.org/10.1126/science.1118391

Abstract

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

Item Type:Article
Subjects:Science > Microbiology > Virology
Veterinary medicine > Veterinary epidemiology. Epizootiology
Live Archive:12 Feb 2024 05:07
Last Modified:12 Feb 2024 05:07

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