Estimation in a multiplicative mixed model involving a genetic relationship matrix.Export / Share PlumX View Altmetrics View AltmetricsKelly, A. M., Cullis, B.R., Gilmour, A.R., Eccleston, J.A. and Thompson, R. (2009) Estimation in a multiplicative mixed model involving a genetic relationship matrix. Genetics Selection Evolution, 41 (1). p. 33.
Article Link: http://dx.doi.org/10.1186/1297-9686-41-33 Publisher URL: http://www.biomedcentral.com/ AbstractGenetic models partitioning additive and non-additive genetic effects for populations tested in replicated multi-environment trials (METs) in a plant breeding program have recently been presented in the literature. For these data, the variance model involves the direct product of a large numerator relationship matrix A, and a complex structure for the genotype by environment interaction effects, generally of a factor analytic (FA) form. With MET data, we expect a high correlation in genotype rankings between environments, leading to non-positive definite covariance matrices. Estimation methods for reduced rank models have been derived for the FA formulation with independent genotypes, and we employ these estimation methods for the more complex case involving the numerator relationship matrix. We examine the performance of differing genetic models for MET data with an embedded pedigree structure, and consider the magnitude of the non-additive variance. The capacity of existing software packages to fit these complex models is largely due to the use of the sparse matrix methodology and the average information algorithm. Here, we present an extension to the standard formulation necessary for estimation with a factor analytic structure across multiple environments.
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