Transgenic gene silencing strategies for virus control.Export / Share PlumX View Altmetrics View AltmetricsDietzgen, R.G. and Mitter, N. (2006) Transgenic gene silencing strategies for virus control. Australasian Plant Pathology, 35 (6). pp. 605-618. Full text not currently attached. Access may be available via the Publisher's website or OpenAccess link. Article Link: http://dx.doi.org/10.1071/AP06064 Publisher URL: http://www.publish.csiro.au AbstractCo-suppression of transgenes and their homologous viral sequences by RNA silencing is a powerful strategy for achieving high-level virus resistance in plants. This review provides a brief overview of RNA silencing mechanisms in plants and discusses important transgene construct design features underpinning successful RNA silencing-mediated transgenic virus control. Application of those strategies to protect horticultural and field crops from virus infection and results of field tests are also provided. The effectiveness and stability of RNA-mediated transgenic resistance are assessed taking into account effects of viral, plant and environmental factors.
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