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The immune gene repertoire of an important viral reservoir, the Australian black flying fox

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Papenfuss, A. T., Baker, M. L., Feng, Z.-P., Tachedjian, M., Crameri, G., Cowled, C., Ng, J., Janardhana, V., Field, H. E. and Wang, L.-F. (2012) The immune gene repertoire of an important viral reservoir, the Australian black flying fox. BMC Genomics, 13 (1). p. 261. ISSN 1471-2164

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Article Link(s): https://doi.org/10.1186/1471-2164-13-261

Abstract

Bats are the natural reservoir host for a range of emerging and re-emerging viruses, including SARS-like coronaviruses, Ebola viruses, henipaviruses and Rabies viruses. However, the mechanisms responsible for the control of viral replication in bats are not understood and there is little information available on any aspect of antiviral immunity in bats. Massively parallel sequencing of the bat transcriptome provides the opportunity for rapid gene discovery. Although the genomes of one megabat and one microbat have now been sequenced to low coverage, no transcriptomic datasets have been reported from any bat species. In this study, we describe the immune transcriptome of the Australian flying fox, Pteropus alecto, providing an important resource for identification of genes involved in a range of activities including antiviral immunity.

Item Type:Article
Subjects:Science > Biology > Genetics
Science > Zoology > Chordates. Vertebrates
Deposited On:28 Sep 2020 05:29
Last Modified:28 Sep 2020 05:29

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