Login | Create Account (DAF staff only)

Prophylactic and therapeutic efficacy of Australian-registered insecticide formulations against Old World screwworm (Chrysomya bezziana) infestation

James, P. J., Wardhana, A. H., Brown, G. W., Mayer, D. G. and Urech, R. (2017) Prophylactic and therapeutic efficacy of Australian-registered insecticide formulations against Old World screwworm (Chrysomya bezziana) infestation. Australian Veterinary Journal, 95 (8). pp. 265-272. ISSN 1751-0813

Full text not currently attached. Access may be available via the Publisher's website or OpenAccess link.

Article Link(s): http://dx.doi.org/10.1111/avj.12609

Abstract

Objective To determine the prophylactic and therapeutic efficacy of Australian-registered insecticide formulations against Old World screwworm (OWS) myiases for potential use in screwworm containment and eradication programs. Methods The longevity of protection provided by six insecticidal formulations (subcutaneous ivermectin, doramectin and abamectin, a topically applied aqueous formulation of spinosad, ivermectin controlled-release capsule and a dicyclanil spray-on formulation) was tested using implants of 1st-instar OWS larvae on Javanese thin-tail sheep. Therapeutic efficacy of four formulations (topical ivermectin, chlorfenvinphos/cypermethrin mixture, aerosol spinosad formulation and a formulation containing propetamphos and eucalyptus oil) was tested against 2- and 4-day-old OWS strikes. Results Both the ivermectin capsule and dicyclanil spray-on formulation gave 100% protection against screwworm implants for the full 12 weeks of the study. Ivermectin, doramectin and abamectin administered SC all gave 100% protection at 3 days post-treatment, but at 2 weeks the protection had become incomplete. Spinosad dipping did not give complete protection at any time. All four therapeutic treatments gave complete resolution of 2-day-old strikes and topical ivermectin, spinosad and chlorfenvinphos/cypermethrin, but not the propetamphos/eucalyptus oil formulation, gave complete resolution of all 4-day-old strikes. Conclusion Dicyclanil spray-on and ivermectin capsule formulations, both registered for use in sheep, but not for cattle or other livestock species, gave much longer protection against screwworm implants than the currently recommended SC ivermectin. Pre-emptive action to facilitate rapid deployment of these formulations in the event of a screwworm incursion is urgently needed.

Item Type:Article
Business groups:Animal Science
Keywords:Calliphoridae dicyclanil macrocyclic lactones myiasis organophosphates screwworms spinosad
Subjects:Science > Entomology
Animal culture > Sheep
Veterinary medicine > Other diseases and conditions
Deposited On:12 Jan 2018 04:25
Last Modified:12 Jan 2018 04:25

Repository Staff Only: item control page