Persistent or long-term coronavirus infection in Australian bats

Abstract

When the World Health Organization declared the end of the global outbreak of severe acute respiratory syndrome (SARS) on the 5 July 2003, more than 8000 cases with over 800 fatalities had been reported in 32 countries worldwide and financial costs to the global economy were close to $US40 billion1,2. Coronaviruses were identified as being responsible for the outbreaks of both SARS and Middle East respiratory syndrome (MERS, the latter in 2013). Subsequently, bats (order Chiroptera) were identified as the natural hosts for a large number of novel and genetically diverse coronaviruses, including the likely ancestors to SARS-like and MERS-like coronaviruses3–8.