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Residue Potential of Norsesquiterpene Glycosides in Tissues of Cattle Fed Austral Bracken (Pteridium esculentum).

Fletcher, M.T. and Reichmann, K.G. and Brock, I.J. and McKenzie, R.A. and Blaney, G.J. (2011) Residue Potential of Norsesquiterpene Glycosides in Tissues of Cattle Fed Austral Bracken (Pteridium esculentum). Journal of Agricultural and Food Chemistry, 59 (15). pp. 8518-8523.

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Article Link(s): http://dx.doi.org/10.1021/jf201342t

Publisher URL: http://pubs.acs.org

Abstract

Austral bracken, Pteridium esculentum, occurs widely in Australian grazing lands and contains both the known carcinogen ptaquiloside and its hydroxy analogue, ptesculentoside, with untested carcinogenic potential. Calves were fed a diet containing 19% P. esculentum that delivered 1.8 mg of ptaquiloside and 4.0 mg of ptesculentoside per kilogram of body weight (bw) per day to explore the carcass residue potential of these compounds. Concentrations of ptaquiloside and ptesculentoside in the liver, kidney, skeletal muscle, heart, and blood of these calves were determined as their respective elimination products, pterosin B and pterosin G, by HPLC-UV analysis. Plasma concentrations of up to 0.97 mu g/mL ptaquiloside and 1.30 mu g/mL ptesculentoside were found, but were shown to deplete to <10% of these values within 24 h of bracken consumption. Both glycosides were also detected in all tissues assayed, with ptesculentoside appearing to be more residual than ptaquiloside. Up to 0.42 and 0.32 mu g/g ptesculentoside was present in skeletal muscle and liver, respectively, 15 days after bracken consumption ended. This detection of residual glycosides in tissues of cattle feeding on Austral bracken raises health concerns for consumers and warrants further investigation.

Item Type:Article
Corporate Creators:Department of Employment, Economic Development & Innovations (DEEDI), Biosecurity Queensland
Business groups:Biosecurity Queensland, QAFFI
Additional Information:© The American Chemical Society
Keywords:Ptaquiloside; ptesculentoside; bracken; Pteridium esculentum; cattle; carcase residues; bracken fern.
Subjects:Animal culture > Cattle
Plant culture > Economic zoology applied to crops. Agricultural zoology
Deposited On:24 Nov 2011 06:20
Last Modified:05 Dec 2011 03:14

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