Experimental Haemonchus contortus infections in guinea pigs

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Wagland, B.M., Abeydeera, L.R., Rothwell, T.L.W. and Ouwerkerk, D. (1989) Experimental Haemonchus contortus infections in guinea pigs. International Journal for Parasitology, 19 (3). pp. 301-305. ISSN 00207519

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Article Link: http://dx.doi.org/10.1016/0020-7519(89)90141-0

Abstract

Approximately 40% of exsheathed Haemonchus contortus larvae administered to guinea pigs established in the stomach and developed into fourth stage larvae. Most worms were then lost between 5 and 7 days after infection and the guinea pigs were resistant to a second infection. Haemorrhage, oedema and infiltration with inflammatory cells, especially eosinophils, developed in the stomach wall of infected guinea pigs and reactive hyperplastic changes occurred in the gastric lymph node. H. contortus infection of guinea pigs has some potential as a model for study of the pathology, immunology and chemotherapy of gastric nematodiasis.

Item Type:	Article
Corporate Creators:	Department of Agriculture and Fisheries, Queensland
Business groups:	Animal Science
Subjects:	Veterinary medicine > Veterinary microbiology Veterinary medicine > Veterinary bacteriology Veterinary medicine > Veterinary parasitology
Live Archive:	02 Oct 2024 04:54
Last Modified:	02 Oct 2024 04:54

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