Hampson, D.J. and Oxberry, S.L. and Stephens, C.P. (2006) Antimicrobial susceptibility testing of Brachyspira intermedia and Brachyspira pilosicoli isolates from Australian chickens. Avian Pathology, 35 (1). pp. 12-16.
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Article Link(s): http://dx.doi.org/10.1080/03079450500465643
Publisher URL: http://www.tandf.co.uk/journals/alphalist.asp
Susceptibilities of predominantly Australian isolates of the pathogenic intestinal spirochaetes Brachyspira intermedia (n=25) and Brachyspira pilosicoli (n=17) from chickens were tested in agar dilution against four concentrations each of the antimicrobials tiamulin, lincomycin, tylosin, metronidazole, tetracycline and ampicillin. Based on available minimum inhibitory concentration (MIC) breakpoint values for Brachyspira hyodysenteriae or other Gram-negative enteric veterinary pathogens, isolates of both species generally were susceptible to tiamulin, lincomycin, metronidazole and tetracycline. Although not classed as resistant, four isolates of B. intermedia had an elevated MIC range for tiamulin (1 to 4 mg/l), 11 isolates of B. intermedia and five of B. pilosicoli had an elevated MIC range for lincomycin (10 to 50 mg/l), one isolate of B. pilosicoli had an elevated MIC range for tetracycline (10 to 20 mg/l), and one isolate of B. intermedia and five of B. pilosicoli had an elevated MIC range for ampicillin (10 to 50 mg/l). A clear lack of susceptibility to tylosin (MIC >4 mg/l) was seen in 11 isolates each of B. intermedia and B. pilosicoli, and to ampicillin (MIC >32 mg/l) in two isolates of B. pilosicoli. These data suggest that some resistance to common antimicrobials exists among intestinal spirochetes obtained from laying hens and supports the need of MIC data for clinical isolates before any treatment is considered.
|Additional Information:||© Taylor & Francis.|
|Keywords:||Serpulina-Hyodysenteriae; Intestinal Spirochetosis; Lincosamide Resistance; Broiler Breeders; Egg-Production; Association; Prevalence; Macrolide; Tiamulin; Flocks.|
|Subjects:||Veterinary medicine > Veterinary pathology|
|Deposited On:||02 Feb 2009 06:53|
|Last Modified:||02 Feb 2009 06:53|
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