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Evolutionary relationships between bat coronaviruses and their hosts

Cui, Y. and Han, N. and Streicker, D. and Li, G. and Tang, X. and Shi, Z. and Hu, Z. and Zhao, A. and Fontanet, A. and Guan, Y. and Wang, L. and Jones, G. and Field, H.E. and Daszak, P. and Zhang, S. (2007) Evolutionary relationships between bat coronaviruses and their hosts. Emerging Infectious Diseases, 131 (10). pp. 1526-1532.

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Article Link(s): http://www.cdc.gov/eid/content/13/10/pdfs/1526.pdf

Publisher URL: http://www.cdc.gov/

Abstract

Recent studies have suggested that bats are the natural reservoir of a range of coronaviruses (CoVs), and that rhinolophid bats harbor viruses closely related to the severe acute respiratory syndrome (SARS) CoV, which caused an outbreak of respiratory illness in humans during 2002-2003. We examined the evolutionary relationships between bat CoVs and their hosts by using sequence data of the virus RNA-dependent RNA polymerase gene and the bat cytochrome b gene. Phylogenetic analyses showed multiple incongruent associations between the phylogenies of rhinolophid bats and their CoVs, which suggested that host shifts have occurred in the recent evolutionary history of this group. These shifts may be due to either virus biologic traits or host behavioral traits. This finding has implications for the emergence of SARS and for the potential future emergence of SARS-CoVs or related viruses.

Item Type:Article
Corporate Creators:Biosecurity Queensland
Additional Information:© Centers for Disease Control and Prevention. Emerging Infectious Diseases is published by the Centers for Disease Control and Prevention, a U.S. Government agency. Therefore, all materials published in Emerging Infectious Diseases are in the public domain and can be used without permission. Proper citation, however, is required.
Keywords:Coronaviruses; Rhinolophid bats; severe acute respiratory syndrome (SARS); CoV; RNA-dependent; RNA polymerase gene; Cytochrome b gene.
Subjects:Science > Biology > Genetics
Science > Zoology > Chordates. Vertebrates > Mammals
Veterinary medicine > Diseases of special classes of animals
Veterinary medicine > Veterinary virology
Deposited On:22 Jan 2009 01:42
Last Modified:23 Nov 2010 22:28

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