Horwood, P.F. and Gravel, J.L. and Mahony, T.J. (2008) Identification of two distinct bovine parainfluenza virus type 3 genotypes. The Journal of general virology, 89 (Pt 7). pp. 1643-1648.
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Article Link(s): http://dx.doi.org/10.1099/vir.0.2008/000026-0
Publisher URL: http://www.sgmjournals.org/
The partial gene sequencing of the matrix (M) protein from seven clinical isolates of bovine parainfluenza virus type 3 (BPIV-3), and the complete sequencing of a representative isolate (Q5592) was completed in this study. Nucleotide sequence analysis was initiated because of the failure of in-house BPIV-3 RT-PCR methods to yield expected products for four of the isolates. Phylogenetic reconstructions based on the nucleotide sequences for the M-protein and the entire genome, using all of the available BPIV-3 nucleotide sequences, demonstrated that there were two distinct BPIV-3 genotypes (BPIV-3a and BPIV-3b). These newly identified genotypes have implications for the development of BPIV-3 molecular detection methods and may also impact on BPIV-3 vaccine formulations.
|Corporate Creators:||Emerging Technologies|
|Additional Information:||© Society for General Microbiology.|
|Keywords:||Matrix protein; Virus RNA; Animal; Cattle; Classification; DNA sequence; Genetics; Genotype; Human; Isolation and purification; Molecular genetics; Parainfluenza Virus 3; Phylogeny; RNA Virus infection; Sequence homology; Virology; Virus genome; Animals; Genome, Viral; Humans; Molecular Sequence Data; Parainfluenza Virus 3, Bovine; Respirovirus Infections; RNA, Viral; Sequence Analysis, DNA; Viral Matrix Proteins.|
|Subjects:||Animal culture > Cattle|
Science > Biology > Genetics
|Deposited On:||13 Feb 2009 04:05|
|Last Modified:||17 Feb 2009 06:49|
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