Drinkwater, R.D. and Lenane, Y.Li,I. and Davis, G.P. and Shorthose, R. and Harrison, B.E. and Richardson, K. and Ferguson, D. and Stevenson, R. and Renaud, J. and Loxton, I. and Hawken, R.J. and Thomas, M.B. and Newman, S. and Hetzel, D.J.S. and Barendse, W. (2006) Detecting quantitative trait loci affecting beef tenderness on bovine chromosome 7 near calpastatin and lysyl oxidase. Australian Journal of Experimental Agriculture, 46 (2). pp. 159-164.
Article Link(s): http://dx.doi.org./10.1071/EA05185
Publisher URL: http://www.publish.csiro.au
From a study of 3 large half-sib families of cattle, we describe linkage between DNA polymorphisms on bovine chromosome 7 and meat tenderness. Quantitative trait loci (QTL) for Longissimus lumborum peak force (LLPF) and Semitendonosis adhesion (STADH) were located to this map of DNA markers, which includes the calpastatin ( CAST) and lysyl oxidase (LOX) genes. The LLPF QTL has a maximum lodscore of 4.9 and allele substitution of approximately 0.80 of a phenotypic standard deviation, and the peak is located over the CAST gene. The STADH QTL has a maximum lodscore of 3.5 and an allele substitution of approximately 0.37 of a phenotypic standard deviation, and the peak is located over the LOX gene. This suggests 2 separate likelihood peaks on the chromosome. Further analyses of meat tenderness measures in the Longissimus lumborum, LLPF and LL compression (LLC), in which outlier individuals or kill groups are removed, demonstrate large shifts in the location of LLPF QTL, as well as confirming that there are indeed 2 QTL on bovine chromosome 7. We found that both QTL are reflected in both LLPF and LLC measurements, suggesting that both these components of tenderness, myofibrillar and connective tissue, are detected by both measurements in this muscle.
|Corporate Creators:||Department of Employment, Economic Development and Innovation (DEEDI), Agri-Science, Crop and Food Science, Animal Science|
|Business groups:||Agri-Science, Crop and Food Science, Animal Science|
|Additional Information:||Reproduced with permission from © CSIRO Publishing. Access to published version may be available via Publisher’s website.|
|Keywords:||Genetic linkage map; meat tenderness; cattle; polymorphisms; DNA; microsatellites; genome.|
|Subjects:||Science > Physiology > Animal biochemistry|
Science > Statistics > Statistical data analysis
Animal culture > Cattle > Meat production
|Deposited On:||13 Jan 2009 03:29|
|Last Modified:||26 Oct 2011 06:14|
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